Human chibby homolog 1 (Drosophila) ELISA Kit | CBY1 elisa kit
Human Protein chibby homolog 1, CBY1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CBY1: Inhibits the Wnt/Wingless pathway by binding to beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. Belongs to the chibby family.
Protein type: Transcription regulation
Chromosomal Location of Human Ortholog: 22q12
Cellular Component: nucleoplasm; nuclear speck; trans-Golgi network; nucleus; cytosol
Molecular Function: identical protein binding; protein binding; beta-catenin binding
Biological Process: fat cell differentiation; protein localization; negative regulation of Wnt receptor signaling pathway; negative regulation of transcription, DNA-dependent; cardiac muscle cell differentiation
Research Articles on CBY1
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Product Notes
The Human CBY1 cby1 (Catalog #AAA9319849) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319849 ELISA Kit recognizes Human CBY1. It is sometimes possible for the material contained within the vial of "chibby homolog 1 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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