Calcineurin B-like protein 1 (CBL1) Recombinant Protein | CBL1 recombinant protein

Recombinant Arabidopsis thaliana Calcineurin B-like protein 1 (CBL1)

Cat. Num. AAA1174578

• Gene Names: CBL1; ARABIDOPSIS THALIANA CALCINEURIN B-LIKE PROTEIN; ATCBL1; calcineurin B-like protein 1; FCAALL.122; SCABP5; SOS3-LIKE CALCIUM BINDING PROTEIN 5
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Calcineurin B-like protein 1 (CBL1); Recombinant Arabidopsis thaliana Calcineurin B-like protein 1 (CBL1); CBL1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-213, Full length protein
• Sequence: GCFHSKAAKEFRGHEDPVKLASETAFSVSEVEALFELFKSISSSVVDDGLINKEEFQLALFKSRKRENIFANRIFDMFDVKRKGVIDFGDFVRSLNVFHPNASLEDKIDFTFRLYDMDCTGYIERQEVKQMLIALLCESEMKLADETIEIILDKTFEDADVNQDGKIDKLEWSDFVNKNPSLLKIMTLPYLRDITTTFPSFVFHSEVDEIAT
• Sequence Length: 212

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 1063723300
• NCBI GeneID: 827481
• NCBI Accession #: NP_001329534.1
• NCBI GenBank Nucleotide #: NM_001341238.1
• UniProt Accession #: O81445; O23603
• Molecular Weight: 24,554 Da
• NCBI Official Full Name: calcineurin B-like protein 1
• NCBI Official Symbol: CBL1
• NCBI Official Synonym Symbols: ARABIDOPSIS THALIANA CALCINEURIN B-LIKE PROTEIN; ATCBL1; calcineurin B-like protein 1; FCAALL.122; SCABP5; SOS3-LIKE CALCIUM BINDING PROTEIN 5
• NCBI Protein Information: calcineurin B-like protein 1
• UniProt Protein Name: Calcineurin B-like protein 1
• Protein Family: Calcineurin B-like protein
• UniProt Gene Name: CBL1
• UniProt Synonym Gene Names: SCABP5

NCBI Description

Member of AtCBL (Calcineurin B-like Calcium Sensor Proteins) family. Protein level is increased upon high salt, mannitol, and cold stresses. CBL1 interacts with CIPK23 and recruits the kinase to the plasma membrane where the substrate(s) of CIPK23 may reside. CBL1 localization is regulated by protein modification including myristolation and acylation.

Uniprot Description

Acts as a calcium sensor involved in the signaling pathway during growth and development and in response to abiotic stresses. May function as a positive regulator of salt and drought responses and as a negative regulator of cold response. Contributes to the regulation of early stress-related CBF/DREB transcription factors. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Involved in response to glucose and gibberellin during germination and seedling development and in response to cold stress. Involved in the calcium-dependent regulation by CIPK26 of reactive oxygen species production by the NADPH oxidase RBOHF.