Cannabinoid Receptor 1 Assay System | CB1 assay system
Cannabinoid Receptor 1 (CB1) ACTOne Stable Cell Line
NCBI and Uniprot Product Information
Uniprot Description
CNR1: Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: growth cone; membrane; intracellular membrane-bound organelle; axon; plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity; signal transducer activity; cannabinoid receptor activity; drug binding
Biological Process: response to nicotine; regulation of synaptic transmission, glutamatergic; negative regulation of fatty acid beta-oxidation; regulation of lipid metabolic process; positive regulation of apoptosis; response to morphine; positive regulation of acute inflammatory response to antigenic stimulus; response to lipopolysaccharide; signal transduction; sensory perception of pain; glucose homeostasis; learning and/or memory; negative regulation of blood pressure; negative regulation of dopamine secretion; aging; negative regulation of mast cell activation; negative regulation of nitric-oxide synthase activity; axonal fasciculation; negative regulation of action potential; response to cocaine; regulation of synaptic transmission, GABAergic; memory; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; response to ethanol; positive regulation of fever; regulation of insulin secretion; negative regulation of ion transport; positive regulation of blood pressure
Research Articles on CB1
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Product Notes
The CB1 cnr1 (Catalog #AAA433637) is an Assay System and is intended for research purposes only. The product is available for immediate purchase. cAMP dependent human CB1 cell-based assay; cell-based high-throughput screening of human CB1 inhibitors. Researchers should empirically determine the suitability of the CB1 cnr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cannabinoid Receptor 1, Assay System" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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