Cat Major Facilitator Superfamily Domain-Containing Protein 8 (MFSD8) ELISA Kit | MFSD8 elisa kit
Cat Major Facilitator Superfamily Domain-Containing Protein 8 (MFSD8) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008]
Uniprot Description
MFSD8: May be a carrier that transport small solutes by using chemiosmotic ion gradients (Potential). Defects in MFSD8 are the cause of neuronal ceroid lipofuscinosis type 7 (CLN7). A form of late infantile neuronal ceroid lipofuscinosis. CNL are a clinically and genetically heterogeneous group of neurodegenerative disorders characterized by the intracellular accumulation of autofluorescent lipopigment storage material in different patterns ultrastructurally. The patterns most often observed CLN7 are mixed combinations of granular, curvilinear, fingerprint, and rectilinear profiles. The clinical course includes progressive dementia, seizures, and progressive visual failure. Belongs to the major facilitator superfamily.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q28.2
Cellular Component: intracellular membrane-bound organelle; lysosomal membrane; nucleoplasm
Disease: Ceroid Lipofuscinosis, Neuronal, 7; Macular Dystrophy With Central Cone Involvement
Research Articles on MFSD8
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Product Notes
The Cat MFSD8 mfsd8 (Catalog #AAA9374642) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9374642 ELISA Kit recognizes Cat MFSD8. It is sometimes possible for the material contained within the vial of "Major Facilitator Superfamily Domain-Containing Protein 8 (MFSD8), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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