Peripheral plasma membrane protein CASK (CASK) Recombinant Protein | CASK recombinant protein

Recombinant Human Peripheral plasma membrane protein CASK (CASK) , partial

• Gene Names: CASK; CMG; FGS4; LIN2; TNRC8; hCASK; CAGH39; CAMGUK; MICPCH; MRXSNA
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Peripheral plasma membrane protein CASK (CASK); Recombinant Human Peripheral plasma membrane protein CASK (CASK); partial; CASK recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 909

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 186700627
• NCBI GeneID: 8573
• NCBI Accession #: NP_001119526.1
• NCBI GenBank Nucleotide #: NM_001126054.2
• UniProt Accession #: O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; A6NES1; B7ZKY0
• Molecular Weight: 103,211 Da
• NCBI Official Full Name: peripheral plasma membrane protein CASK isoform 2
• NCBI Official Synonym Full Names: calcium/calmodulin dependent serine protein kinase
• NCBI Official Symbol: CASK
• NCBI Official Synonym Symbols: CMG; FGS4; LIN2; TNRC8; hCASK; CAGH39; CAMGUK; MICPCH; MRXSNA
• NCBI Protein Information: peripheral plasma membrane protein CASK
• UniProt Protein Name: Peripheral plasma membrane protein CASK
• Protein Family: Peripheral plasma membrane protein
• UniProt Gene Name: CASK
• UniProt Synonym Gene Names: LIN2; hCASK

NCBI Description

This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, intellectual disability and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked intellectual disability. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]

Uniprot Description

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.