Cysteine--tRNA ligase, cytoplasmic (CARS) Recombinant Protein | CARS recombinant protein

Recombinant Human Cysteine--tRNA ligase, cytoplasmic (CARS)

Cat. Num. AAA961027

• Gene Names: CARS; CARS1; CYSRS; MGC:11246
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cysteine--tRNA ligase; cytoplasmic (CARS); Recombinant Human Cysteine--tRNA ligase; CARS recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-748, Full length protein
• Sequence: ADSSGQQGKGRRVQPQWSPPAGTQPCRLHLYNSLTRNKEVFIPQDGKKVTWYCCGPTVYDASHMGHARSYISFDILRRVLKDYFKFDVFYCMNITDIDDKIIKRARQNHLFEQYREKRPEAAQLLEDVQAALKPFSVKLNETTDPDKKQMLERIQHAVQLATEPLEKAVQSRLTGEEVNSCVEVLLEEAKDLLSDWLDSTLGCDVTDNSIFSKLPKFWEGDFHRDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGYGYVSNGSVYFDTAKFASSEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSEKRSPNDFALWKASKPGEPSWPCPWGKGRPGWHIECSAMAGTLLGASMDIHGGGFDLRFPHHDNELAQSEAYFENDCWVRYFLHTGHLTIAGCKMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTMESALQYEKFLNEFFLNVKDILRAPVDITGQFEKWGEEEAELNKNFYDKKTAIHKALCDNVDTRTVMEEMRALVSQCNLYMAARKAVRKRPNQALLENIALYLTHMLKIFGAVEEDSSLGFPVGGPGTSLSLEATVMPYLQVLSEFREGVRKIAREQKVPEILQLSDALRDNILPELGVRFEDHEGLPTVVKLVDRNTLLKEREEKRRVEEEKRKKKEEAARRKQEQEAAKLAKMKIPPSEMFLSETDKYSKFDENGLPTHDMEGKELSKGQAKKLKKLFEAQEKLYKEYLQMAQNGSFQ
• Sequence Length: 747

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for CARS recombinant protein

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

NCBI and Uniprot Product Information

• NCBI GI #: 62240992
• NCBI GeneID: 833
• NCBI Accession #: NP_001014437.1
• NCBI GenBank Nucleotide #: NM_001014437.2
• UniProt Accession #: P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25
• Molecular Weight: 94,638 Da
• NCBI Official Full Name: cysteine--tRNA ligase, cytoplasmic isoform c
• NCBI Official Synonym Full Names: cysteinyl-tRNA synthetase
• NCBI Official Symbol: CARS
• NCBI Official Synonym Symbols: CARS1; CYSRS; MGC:11246
• NCBI Protein Information: cysteine--tRNA ligase, cytoplasmic
• UniProt Protein Name: Cysteine--tRNA ligase, cytoplasmic
• Protein Family: CDP-archaeol synthase
• UniProt Gene Name: CARS
• UniProt Synonym Gene Names: CysRS

NCBI Description

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]