Uniprot Description
Function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC.
Pathway: Capsule biogenesis; capsule polysaccharide biosynthesis.
Subcellular location: Cell membrane; Single-pass membrane protein.
Induction: Capsule synthesis is transcriptionally regulated by AtxA, AcpA and AcpB. Ref.6
Sequence similarities: Belongs to the CapA family.
Product Notes
The pxo2_56 capa (Catalog #
AAA1058011) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-411. The amino acid sequence is listed below: MRRKLTFQEK LLIFIKKTKK KNPRYVAIVL PLIAVILIAA TWVQRTEAVA PVKHRENEKL TMTMVGDIMM GRHVKEIVNR YGTDYVFRHV SPYLKNSDYV SGNFEHPVLL EDKKNYQKAD KNIHLSAKEE TVKAVKEAGF TVLNLANNHM TDYGAKGTKD TIKAFKEADL DYVGAGENFK DVKNIVYQNV NGVRVATLGF TDAFVAGAIA TKEQPGSLSM NPDVLLKQIS KAKDPKKGNA DLVVVNTHWG EEYDNKPSPR QEALAKAMVD AGADIIVGHH PHVLQSFDVY KQGIIFYSLG NFVFDQGWTR TKDSALVQYH LRDNGTAILD VVPLNIQEGS PKPVTSALDK NRVYRQLTKD TSKGALWSKK DDKLEIKLNH KHVIEKMKKR EKQEHQDKQE KENQVSVETT T.
It is sometimes possible for the material contained within the vial of
"Capsule biosynthesis protein CapA (capA), Recombinant Protein" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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