Complement C1q Tumor Necrosis Factor-Related Protein 1 Recombinant Protein | C1QTNF1 recombinant protein
Recombinant Human Complement C1q Tumor Necrosis Factor-Related Protein 1
Gene Names
C1QTNF1; GIP; CTRP1; ZSIG37
Purity
Greater than 95% as determined by SDS PAGE.
Synonyms
Complement C1q Tumor Necrosis Factor-Related Protein 1; Recombinant Human Complement C1q Tumor Necrosis Factor-Related Protein 1; C1QTNF1 Human; Complement C1q Tumor Necrosis Factor-Related Protein 1 Human Recombinant; GIP; CTRP1; ZSIG37; FLJ90694; C1QTNF1; G protein-coupled receptor-interacting protein; C1QTNF1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS PAGE.
Form/Format
Human C1QTNF1 was lyophilized from 50mM Acetate Buffer pH-4.
Sequence
MKHHHHHHAS RVPHVQGEQQ EWEGTEELPS PPDHAERAEE QHEKYRPSQD QGLPASRCLR CCDPGTSMYP ATAVPQINIT ILKGEKGDRG DRGLQGKYGK TGSAGARGHT GPKGQKGSMG APGERCKSHY AAFSVGRKKP MHSNHYYQTV IFDTEFVNLY DHFNMFTGKF YCYVPGLYFF SLNVHTWNQK ETYLHIMKNE EEVVILFAQV GDRSIMQSQS LMLELREQDQ VWVRLYKGER ENAIFSEELD TYITFSGYLVKHATEP
Sequence Length
281
Solubility
Add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10ug/ml. In higher concentrations the solubility of this antigen is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Preparation and Storage
Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
Related Product Information for C1QTNF1 recombinant protein
Description: C1QTNF1 Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 266 amino acids and having a molecular mass of 30.45 kDa. The protein contains an extra His tag at N-terminus. The C1QTNF1 amino acid sequence is identical to UniProtKB/Swiss-Prot entry Q9BXJ1 amino acids 26281.The C1QTNF1 is purified by proprietary chromatographic techniques.
Introduction: C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.
Introduction: C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.
Product Categories/Family for C1QTNF1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,760 Da
NCBI Official Full Name
complement C1q tumor necrosis factor-related protein 1 isoform 1
NCBI Official Synonym Full Names
C1q and tumor necrosis factor related protein 1
NCBI Official Symbol
C1QTNF1
NCBI Official Synonym Symbols
GIP; CTRP1; ZSIG37
NCBI Protein Information
complement C1q tumor necrosis factor-related protein 1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein
UniProt Protein Name
Complement C1q tumor necrosis factor-related protein 1
Protein Family
UniProt Gene Name
C1QTNF1
UniProt Synonym Gene Names
CTRP1; GIP
UniProt Entry Name
C1QT1_HUMAN
Uniprot Description
C1QTNF1: 2 isoforms of the human protein are produced by alternative splicing
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: extracellular space; collagen; integral to plasma membrane
Molecular Function: collagen binding; protein binding
Biological Process: positive regulation of protein kinase B signaling cascade; elevation of cytosolic calcium ion concentration; positive regulation of MAPKKK cascade; protein homooligomerization
Research Articles on C1QTNF1
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Product Notes
The C1QTNF1 c1qtnf1 (Catalog #AAA143413) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MKHHHHHHAS RVPH VQGEQQ EWEGTEELPS PPDHAERAEE QHEKYRPSQD QGLPASRCLR CCDPGTSMYP ATAVPQINIT ILKGEKGDRG DRGLQGKYGK TGSAGARGHT GPKGQKGSMG APGERCKSHY AAFSVGRKKP MHSNHYYQTV IFDTEFVNLY DHFNMFTGKF YCYVPGLYFF SLNVHTWNQK ETYLHIMKNE EEVVILFAQV GDRSIMQSQS LMLELREQDQ VWVRLYKGER ENAIFSEELD TYITFSGYLV KHATEP. It is sometimes possible for the material contained within the vial of "Complement C1q Tumor Necrosis Factor-Related Protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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