Typical Testing Data/Standard Curve (for reference only)
Mouse Complement Component 1 Q Receptor ELISA Kit | C1qR1 elisa kit
Mouse Complement Component 1 Q Receptor ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
INTENDED USE This C1QR ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Mouse C1QR. This ELISA kit for research use only!
PRINCIPLE OF THE ASSAY C1QR ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-C1QR antibody and an C1QR-HRP conjugate. The assay sample and buffer are incubated together with C1QR-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the C1QR concentration since C1QR from samples and C1QR-HRP conjugate compete for the anti-C1QR antibody binding site. Since the number of sites is limited, as more sites are occupied by C1QR from the sample, fewer sites are left to bind C1QR-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The C1QR concentration in each sample is interpolated from this standard curve.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]
Uniprot Description
CD93: Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: cell surface; cytoplasmic membrane-bound vesicle; plasma membrane; integral to membrane
Molecular Function: protein binding; complement component C1q binding; receptor activity; calcium ion binding; carbohydrate binding
Biological Process: macrophage activation; cell-cell adhesion; viral reproduction; phagocytosis
Research Articles on C1qR1
Similar Products
Product Notes
The Mouse C1qR1 cd93 (Catalog #AAA726892) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA726892 ELISA Kit recognizes Mouse C1qR1. It is sometimes possible for the material contained within the vial of "Complement Component 1 Q Receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
