Human chromosome 1 open reading frame 190 ELISA Kit | C1orf190 elisa kit
Human NF-kappa-B activator C1orf190, C1orf190 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
1520402A15Rik: Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella.
Protein type: Contractile; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1p34
Cellular Component: cytoplasm; actomyosin
Biological Process: positive regulation of cytokine production; cell migration; positive regulation of I-kappaB kinase/NF-kappaB cascade; actomyosin structure organization and biogenesis
Research Articles on C1orf190
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Product Notes
The Human C1orf190 lurap1 (Catalog #AAA9319149) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319149 ELISA Kit recognizes Human C1orf190. It is sometimes possible for the material contained within the vial of "chromosome 1 open reading frame 190, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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