Protein BTG3 (Btg3) Recombinant Protein | Btg3 recombinant protein
Recombinant Mouse Protein BTG3 (Btg3)
Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes B cell translocation gene 3, a member of the BTG gene family. This family is defined by a conserved N-terminal domain, known to bind transcription factors, and a less conserved C-terminal domain. This protein is thought to have anti-proliferative properties, and may be involved in regulating the G1-S transition to suppress cell cycle progression. Mice deficient for this gene display an increased incidence of lung cancers, and many human lung cancer cells exhibit decreased levels of B cell translocation gene 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 17. [provided by RefSeq, Jul 2014]
Uniprot Description
Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.
Research Articles on Btg3
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Product Notes
The Btg3 btg3 (Catalog #AAA957291) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-252, Full length protein. The amino acid sequence is listed below: MKNEIAAVVF FFTRLVRKHD KLKKEAVERF AEKLTQILQE KYKNHWYPEK PSKGQAYRCI RVNKFQRVDP DVLKACENSC ILYSDLGLPK ELTLWVDPCE VCCRYGEKNN AFIVASFENE DENKDEISKK VSRALDKVTS DYHSGSSSSD EDTSKEVDVK PSSVAATPSP VYQISELIFP PLPMWHPLPR KKPGMYRGSG HQTHYPPPVP FAYPNPGRKN KPFRPIPVTW VPPPGMHCDR NHWINPHMLA PH. It is sometimes possible for the material contained within the vial of "Protein BTG3 (Btg3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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