CD157 (BST1) Recombinant Protein | CD157 recombinant protein

Human CD157 Recombinant (BST1)

Cat. Num. AAA553159

• Purity: >97%, as determined by SDS-PAGE and HPLC
• Synonyms: CD157 (BST1); Human CD157 Recombinant (BST1); Human CD157 Recombinant (BST1) ; CD157; BST1; CD157 recombinant protein

• Host: HEk293 Cells
• Purity/Purification: >97%, as determined by SDS-PAGE and HPLC
• Form/Format: Recombinant CD157 is supplied as a 0.2 um filtered PBS solution, pH7.2.
• Sequence Length: 318

• Domain: Ig-like C2
• Host Note: Optimized DNA sequence encoding Human extracellular domain of human ADP-ribosyl cyclase CD157 including a C-terminal 6His tag was expressed in HEK293 cells.
• Endotoxin: Endotoxin content was assayed using a LAL gel clot method.; Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
• Molecular Weight Note: Recombinant CD157 is a monomer protein consisting of 275 amino acid residue subunits, due to glycosylation migrates as an approximately 38-43 kDa protein on SDS-PAGE.
• Preparation and Storage: Recombinant CD157, as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.; ; Avoid repeated freeze/thaw cycles.

Related Product Information for CD157 recombinant protein

CD157, a member of the CD38 gene family, is an NAD- metabolizing ectoenzyme and a signaling molecule whose role in polarization, migration, and diapedesis of human granulocytes has been documented. Ectoenzymes include a heterogeneous group of surface molecules with multiple functions. In addition to interacting with specific substrates, many of them participate in leukocyte activation and migration. In some cases, ectoenzymes exert enzymatic control of leukocyte trafficking. Along with CD38, human CD157 constitutes the NAD glycohydrolase/ADP-ribosyl cyclase gene family. These two molecules share 36% of their protein sequence, including 10 cysteine residues forming intrachain disulfide bonds. However, they differ in structure, with CD157 being a glycosylphosphatidylinositol

Product Categories/Family for CD157 recombinant protein

Receptors CD

References

• CD157 plays a pivotal role in neutrophil transendothelial migration .Blood, Dec 2006; 108: 4214 - 4222.
• selective upregulation of the adp-ribosyl cyclases cd38 and CD157 by tnf but not by rank-l reveals differences in downstream signaling .Am J Physiol Renal Physiol, Sep 2006; 291: F557 - F566.
• CD157 is an important mediator of neutrophil adhesion and migration .Blood, Dec 2004; 104: 4269 - 4278.