TROVE Domain Family Native Protein | bTROVE2 native protein
Bovine TROVE Domain Family, Member 2
Gene Names
TROVE2; RO60; SSA2; RORNP
Applications
Western Blot, ELISA
Purity
Greater than 60% as determined by SDS-PAGE.
Synonyms
TROVE Domain Family; Bovine TROVE Domain Family; Member 2; TROVE2 Bovine; Bovine; 60 kDa SS-A/Ro ribonucleoprotein; 60 kDa ribonucleoprotein Ro; RoRNP; 60 kDa Ro protein; Ro 60 kDa autoantigen; TROVE domain family member 2; Sjoegren syndrome type A antigen; SS-A; Sjoegren syndrome antigen A2; TROVE2; RO60; SSA2; RO-60; bTROVE2 native protein
Host
Bovine tissues
Purity/Purification
Greater than 60% as determined by SDS-PAGE.
Form/Format
TROVE2 is supplied in 16mM HEPES buffer pH-8.0, 400mM NaCl, and 20% glycerol.
Concentration
0.2-0.6 ug/ml (depending on the type of ELISA plate and coating buffer). Suitable for biotinylation and iodination. (varies by lot)
Sequence Length
538
Applicable Applications for bTROVE2 native protein
Western Blot (WB), ELISA (EIA), Immunodot
Application Notes
Western blot with SLE sera (secondary Sjogren's syndrome).
Immunological Tests: Standard ELISA test (checkerboard analysis of positive/negative sera panels); immunodot test with positive/negative sera panels.
Immunological Tests: Standard ELISA test (checkerboard analysis of positive/negative sera panels); immunodot test with positive/negative sera panels.
Immunological Functions
Binds IgG-type human auto-antibodies.
Related Product Information for bTROVE2 native protein
Introduction: Ro 60 kDa autoantigen is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. SSA2 may stabilize these RNAs from degradation. Sera taken from patients with Systemic Lupus Erythematosus (SLE) often contains antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.
Product Categories/Family for bTROVE2 native protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
59,270 Da
NCBI Official Full Name
TROVE domain family, member 2
NCBI Official Synonym Full Names
TROVE domain family, member 2
NCBI Official Symbol
TROVE2
NCBI Official Synonym Symbols
RO60; SSA2; RORNP
NCBI Protein Information
60 kDa SS-A/Ro ribonucleoprotein; 60 kDa ribonucleoprotein Ro; Sjogren syndrome antigen A2 (60kD, ribonucleoprotein autoantigen SS-A/Ro); gastric cancer multi-drug resistance protein; sjoegren syndrome type A antigen
UniProt Protein Name
60 kDa SS-A/Ro ribonucleoprotein
UniProt Gene Name
TROVE2
UniProt Synonym Gene Names
RO60; SSA2; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; RoRNP; SS-A
UniProt Entry Name
RO60_HUMAN
Uniprot Description
SSA2: RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation. Belongs to the Ro 60 kDa family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 1q31
Cellular Component: nucleoplasm; cytoplasm; ribonucleoprotein complex
Molecular Function: RNA binding; metal ion binding; U2 snRNA binding
Biological Process: transcription from RNA polymerase III promoter; immune system development; smoothened signaling pathway; response to UV
Disease: Heart Block, Congenital
Research Articles on bTROVE2
Similar Products
Product Notes
The bTROVE2 trove2 (Catalog #AAA145441) is a Native Protein produced from Bovine tissues and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TROVE Domain Family can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunodot. Western blot with SLE sera (secondary Sjogren's syndrome). Immunological Tests: Standard ELISA test (checkerboard analysis of positive/negative sera panels); immunodot test with positive/negative sera panels. Researchers should empirically determine the suitability of the bTROVE2 trove2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TROVE Domain Family, Native Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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