Bovine Cytochrome b reductase 1 (CYBRD1) ELISA Kit | CYBRD1 elisa kit
Bovine Cytochrome b reductase 1 (CYBRD1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]
Uniprot Description
CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; EC 1.-.-.-; Transporter, iron; Oxidoreductase; Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: brush border membrane; plasma membrane; integral to membrane
Molecular Function: oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity
Biological Process: cellular iron ion homeostasis; response to iron ion; transmembrane transport
Research Articles on CYBRD1
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Product Notes
The Bovine CYBRD1 cybrd1 (Catalog #AAA7232437) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7232437 ELISA Kit recognizes Bovine CYBRD1. It is sometimes possible for the material contained within the vial of "Cytochrome b reductase 1 (CYBRD1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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