Bovine BCL2-associated X protein ELISA Kit | BAX elisa kit
Bovine Apoptosis regulator BAX, BAX ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. BAX deficiency leads to lymphoid hyperplasia and male sterility, because of the cessation of sperm production