Aprotinin Active Protein | BPI active protein
Bovine Aprotinin
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Aprotinin; Bovine Aprotinin; Pancreatic trypsin inhibitor; Basic protease inhibitor; BPI; BPTI; AP; bAprotinin; BPI active protein
Host
Bovine Lung
Purity/Purification
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
The protein (1mg/ml) was lyophilized with no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence Length
100
Unit Defenition
1 Unit corresponds to 1 biological kallikrein inhibitor unit (KIU)1 TIU =1,300 KIU.
Solubility
It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Activity
6,246 KIU (Kallikrein Inactivator Units) per mg, 3.47 TIU/mg.
Preparation and Storage
Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Aprotinin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Related Product Information for BPI active protein
Description: Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids {C 284 H 432 N 84 O 79 S 7} arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512.
Introduction: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
Introduction: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
Product Categories/Family for BPI active protein
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
10,903 Da
NCBI Official Full Name
Pancreatic trypsin inhibitor
UniProt Protein Name
Pancreatic trypsin inhibitor
Protein Family
UniProt Gene Name
BPI
UniProt Synonym Gene Names
BPTI
UniProt Entry Name
BPT1_BOVIN
Uniprot Description
Inhibits trypsin, kallikrein, chymotrypsin, and plasmin.
Similar Products
Product Notes
The Aprotinin bpi (Catalog #AAA142841) is an Active Protein produced from Bovine Lung and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Aprotinin, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
