Bone morphogenetic protein receptor type-1B Recombinant Protein | Bmpr1b recombinant protein
Bone morphogenetic protein receptor type-1B
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Uniprot Description
BMPR1B: a kinase of the STKR family. A type I cell-surface receptor for bone morphogenetic protein. Expressed at ighest level in the prostate. May be upregulated by androgen stimulation in cells which expresses the androgen receptor.
Protein type: Protein kinase, TKL; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); Kinase, protein; EC 2.7.11.30; TKL group; STKR family; Type1 subfamily
Cellular Component: plasma membrane
Molecular Function: ATP binding; glycoprotein binding; protein binding; protein serine/threonine kinase activity; SMAD binding; transforming growth factor beta receptor activity; transforming growth factor beta receptor activity, type I; transmembrane receptor protein serine/threonine kinase activity
Biological Process: BMP signaling pathway; camera-type eye development; cartilage condensation; cell differentiation; chondrocyte differentiation; dorsal/ventral pattern formation; eye development; limb morphogenesis; ovarian cumulus expansion; ovulation cycle; positive regulation of bone mineralization; positive regulation of cell differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; retina development in camera-type eye; retinal ganglion cell axon guidance; skeletal development; transforming growth factor beta receptor signaling pathway; transmembrane receptor protein serine/threonine kinase signaling pathway
Research Articles on Bmpr1b
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Product Notes
The Bmpr1b bmpr1b (Catalog #AAA7042362) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 14-502aa; full length protein. The amino acid sequence is listed below: KKEDGESTAP TPRPKILRCK CHHHCPEDSV NNICSTDGYC FTMIEEDDSG MPVVTSGCLG LEGSDFQCRD TPIPHQRRSI ECCTERNECN KDLHPTLPPL KDRDFVDGPI HHKALLISVT VCSLLLVLII LFCYFRYKRQ EARPRYSIGL EQDETYIPPG ESLRDLIEQS QSSGSGSGLP LLVQRTIAKQ IQMVKQIGKG RYGEVWMGKW RGEKVAVKVF FTTEEASWFR ETEIYQTVLM RHENILGFIA ADIKGTGSWT QLYLITDYHE NGSLYDYLKS TTLDAKSMLK LAYSSVSGLC HLHTEIFSTQ GKPAIAHRDL KSKNILVKKN GTCCIADLGL AVKFISDTNE VDIPPNTRVG TKRYMPPEVL DESLNRNHFQ SYIMADMYSF GLILWEIARR CVSGGIVEEY QLPYHDLVPS DPSYEDMREI VCMKKLRPSF PNRWSSDECL RQMGKLMTEC WAQNPASRLT ALRVKKTLAK MSESQDIKL. It is sometimes possible for the material contained within the vial of "Bone morphogenetic protein receptor type-1B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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