ZNF207 blocking peptide
ZNF207 Antibody (N-term) Blocking Peptide
Gene Names
ZNF207; BuGZ; hBuGZ
Synonyms
ZNF207; ZNF207 Antibody (N-term) Blocking Peptide; BUB3-interacting and GLEBS motif-containing protein ZNF207; BuGZ; Zinc finger protein 207; BUGZ; ZNF207 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
478
Cellular Location
Nucleus. Chromosome, centromere, kinetochore. Note: Localizes primarily to the nucleus in interphase, concentrates at kinetochores prior to nuclear envelope breakdown and during early prometaphase, and disappears from kinetochores upon microtubule-binding
Tissue Location
Ubiquitous.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ZNF207 blocking peptide
Kinetochore-binding protein involved in spindle-assembly checkpoint signaling by regulating mitotic chromosome alignment and mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 (PubMed:24462186). According to another report, the stabilization is independent of the proteasome (PubMed:24462187).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
52,694 Da
NCBI Official Full Name
BUB3-interacting and GLEBS motif-containing protein ZNF207
NCBI Official Synonym Full Names
zinc finger protein 207
NCBI Official Symbol
ZNF207
NCBI Official Synonym Symbols
BuGZ; hBuGZ
NCBI Protein Information
BUB3-interacting and GLEBS motif-containing protein ZNF207
UniProt Protein Name
BUB3-interacting and GLEBS motif-containing protein ZNF207
Protein Family
UniProt Gene Name
ZNF207
UniProt Synonym Gene Names
hBuGZ
UniProt Entry Name
ZN207_HUMAN
Uniprot Description
ZNF207: 3 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; Spliceosome; Transcription factor
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: kinetochore; nucleolus; nucleus
Molecular Function: microtubule binding; protein binding
Biological Process: attachment of spindle microtubules to kinetochore; microtubule bundle formation; microtubule polymerization; mitotic cell cycle spindle assembly checkpoint; mitotic sister chromatid segregation; protein stabilization; regulation of chromosome segregation
Research Articles on ZNF207
Similar Products
Product Notes
The ZNF207 znf207 (Catalog #AAA9220739) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZNF207, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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