Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

ZMYND11 blocking peptide

ZMYND11 Antibody (N-term) Blocking Peptide

Gene Names
ZMYND11; BS69; BRAM1; MRD30
Synonyms
ZMYND11; ZMYND11 Antibody (N-term) Blocking Peptide; Zinc finger MYND domain-containing protein 11; Adenovirus 5 E1A-binding protein; Bone morphogenetic protein receptor-associated molecule 1; Protein BS69; BRAM1; BS69; ZMYND11 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human ZMYND11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
602
Cellular Location
Nucleus. Chromosome. Note: Associates with chromatin and mitotic chromosomes
Tissue Location
Ubiquitous..
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ZMYND11 blocking peptide
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
66,519 Da
NCBI Official Full Name
Zinc finger MYND domain-containing protein 11
NCBI Official Synonym Full Names
zinc finger MYND-type containing 11
NCBI Official Symbol
ZMYND11
NCBI Official Synonym Symbols
BS69; BRAM1; MRD30
NCBI Protein Information
zinc finger MYND domain-containing protein 11
UniProt Protein Name
Zinc finger MYND domain-containing protein 11
UniProt Gene Name
ZMYND11
UniProt Synonym Gene Names
BRAM1; BS69
UniProt Entry Name
ZMY11_HUMAN

NCBI Description

The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

ZMYND11: Corepressor of transcription (Probable).

Protein type: Transcription regulation; Tumor suppressor; DNA-binding

Chromosomal Location of Human Ortholog: 10p14

Cellular Component: nucleoplasm; nucleus

Molecular Function: chromatin binding; histone binding; methylated histone residue binding; protein binding; transcription cofactor activity; transcription corepressor activity; zinc ion binding

Biological Process: cell proliferation; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of JNK cascade; negative regulation of transcription from RNA polymerase II promoter

Disease: Mental Retardation, Autosomal Dominant 30

Research Articles on ZMYND11

Similar Products

Product Notes

The ZMYND11 zmynd11 (Catalog #AAA9227727) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZMYND11, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.