WNT2B blocking peptide

WNT2B Blocking Peptide

Cat. Num. AAA9621243

• Gene Names: WNT2B; WNT13
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: WNT2B; WNT2B Blocking Peptide; Protein Wnt-13; Protein Wnt-2b; Wingless type MMTV integration site family; member 13; member 2B; WNT13; Wnt2b; WNT2B_HUMAN; XWNT2; Xenopus; homolog of; WNT2B blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for WNT2B blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for WNT2B blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 14424481
• NCBI GeneID: 7482
• UniProt Accession #: Q93097; O14903; Q5TEH9; Q5TEI2; Q9HDC1; Q9HDC2
• Molecular Weight: 41,830 Da
• NCBI Official Full Name: Protein Wnt-2b
• NCBI Official Synonym Full Names: wingless-type MMTV integration site family, member 2B
• NCBI Official Symbol: WNT2B
• NCBI Official Synonym Symbols: WNT13
• NCBI Protein Information: protein Wnt-2b; XWNT2, Xenopus, homolog of; wingless-type MMTV integration site family, member 13
• UniProt Protein Name: Protein Wnt-2b
• Protein Family: Protein
• UniProt Gene Name: WNT2B
• UniProt Synonym Gene Names: WNT13
• UniProt Entry Name: WNT2B_HUMAN

NCBI Description

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Uniprot Description

WNT2B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: frizzled binding

Biological Process: neuron differentiation; lens development in camera-type eye; Wnt receptor signaling pathway; cell fate commitment; male gonad development; chondrocyte differentiation; Wnt receptor signaling pathway through beta-catenin; forebrain regionalization; cellular response to starvation