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WIPF2 blocking peptide

WIPF2 Antibody (C-term) Blocking peptide

Gene Names
WIPF2; WICH; WIRE
Synonyms
WIPF2; WIPF2 Antibody (C-term) Blocking peptide; WAS/WASL-interacting protein family member 2; WASP-interacting protein-related protein; WIP- and CR16-homologous protein; WIP-related protein; WICH; WIRE; WIPF2 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
440
Cellular Location
Cytoplasm, cytoskeleton Note: Localized to stress fibers and bundles of actin filaments
Tissue Location
Expressed mainly in brain, colon, lung and stomach (at protein level). Ubiquitously expressed, with high expression in brain, kidney, lung, and placenta
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for WIPF2 blocking peptide
Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
30,840 Da
NCBI Official Full Name
WAS/WASL-interacting protein family member 2
NCBI Official Synonym Full Names
WAS/WASL interacting protein family member 2
NCBI Official Symbol
WIPF2
NCBI Official Synonym Symbols
WICH; WIRE
NCBI Protein Information
WAS/WASL-interacting protein family member 2
UniProt Protein Name
WAS/WASL-interacting protein family member 2
UniProt Gene Name
WIPF2
UniProt Synonym Gene Names
WICH; WIRE
UniProt Entry Name
WIPF2_HUMAN

NCBI Description

This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery. [provided by RefSeq, Jul 2008]

Uniprot Description

WIRE: Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system. Belongs to the verprolin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: actin filament; cytosol

Molecular Function: actin filament binding; protein binding

Biological Process: actin cortical patch assembly; actin cortical patch localization; actin filament-based movement; endocytosis; positive regulation of actin nucleation; regulation of cell shape

Research Articles on WIPF2

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Product Notes

The WIPF2 wipf2 (Catalog #AAA9218021) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "WIPF2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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