UGT2B11 blocking peptide

UGT2B11 Antibody (C-term) Blocking peptide

• Synonyms: UGT2B11; UGT2B11 Antibody (C-term) Blocking peptide; UDP-glucuronosyltransferase 2B11; UDPGT 2B11; UGT2B11 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the C-term region of UGT2B11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 529

• Cellular Location: Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
• Tissue Location: Widely expressed.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for UGT2B11 blocking peptide

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

NCBI and Uniprot Product Information

• NCBI GI #: 19924288
• NCBI GeneID: 10720
• UniProt Accession #: O75310; Q3KNV9
• Molecular Weight: 61,038 Da
• NCBI Official Full Name: UDP-glucuronosyltransferase 2B11
• NCBI Official Synonym Full Names: UDP glucuronosyltransferase family 2 member B11
• NCBI Official Symbol: UGT2B11
• NCBI Protein Information: UDP-glucuronosyltransferase 2B11
• UniProt Protein Name: UDP-glucuronosyltransferase 2B11
• Protein Family: UDP-glucuronosyltransferase
• UniProt Gene Name: UGT2B11
• UniProt Synonym Gene Names: UDPGT 2B11
• UniProt Entry Name: UDB11_HUMAN

Uniprot Description

UGT2B11: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family.

Protein type: Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Carbohydrate Metabolism - pentose and glucuronate interconversions; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.4.1.17; Carbohydrate Metabolism - ascorbate and aldarate; Carbohydrate Metabolism - starch and sucrose; Lipid Metabolism - androgen and estrogen; Xenobiotic Metabolism - drug metabolism - other enzymes; Transferase

Chromosomal Location of Human Ortholog: 4q13.2

Cellular Component: intracellular membrane-bound organelle

Molecular Function: glucuronosyltransferase activity

Biological Process: estrogen metabolic process; flavonoid biosynthetic process; xenobiotic metabolic process