TOMM34 blocking peptide

TOMM34 Blocking Peptide (Center)

• Gene Names: TOMM34; TOM34; URCC3; HTOM34P
• Synonyms: TOMM34; TOMM34 Blocking Peptide (Center); Mitochondrial import receptor subunit TOM34; hTom34; Translocase of outer membrane 34 kDa subunit; URCC3; TOMM34 blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 156-168 of HUMAN TOMM34
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 309

• Cellular Location: Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side
• Tissue Location: Ubiquitous.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TOMM34 blocking peptide

Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state.

NCBI and Uniprot Product Information

• NCBI GI #: 24212065
• NCBI GeneID: 10953
• UniProt Accession #: Q15785; Q53GH9; Q6IBN7; Q9NTZ3
• Molecular Weight: 34,559 Da
• NCBI Official Full Name: Mitochondrial import receptor subunit TOM34
• NCBI Official Synonym Full Names: translocase of outer mitochondrial membrane 34
• NCBI Official Symbol: TOMM34
• NCBI Official Synonym Symbols: TOM34; URCC3; HTOM34P
• NCBI Protein Information: mitochondrial import receptor subunit TOM34
• UniProt Protein Name: Mitochondrial import receptor subunit TOM34
• Protein Family: Mitochondrial import receptor
• UniProt Gene Name: TOMM34
• UniProt Synonym Gene Names: URCC3; hTom34
• UniProt Entry Name: TOM34_HUMAN

NCBI Description

The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats. [provided by RefSeq, Jul 2008]

Uniprot Description

TOMM34: Plays a role in the import of cytosolically synthesized preproteins into mitochondria. Binds the mature portion of precursor proteins. Interacts with cellular components, and possesses weak ATPase activity. May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state. Belongs to the Tom34 family.

Protein type: Chaperone; Mitochondrial

Chromosomal Location of Human Ortholog: -

Cellular Component: cytoplasm; integral to membrane; membrane; mitochondrial outer membrane; nucleoplasm; nucleus

Molecular Function: heat shock protein binding; protein binding

Biological Process: protein targeting to mitochondrion