TBC1D2 blocking peptide
TBC1D2 Antibody (Center) Blocking Peptide
Gene Names
TBC1D2; PARIS1; PARIS-1; TBC1D2A
Synonyms
TBC1D2; TBC1D2 Antibody (Center) Blocking Peptide; TBC1 domain family member 2A; Armus; Prostate antigen recognized and identified by SEREX 1; PARIS-1; PARIS1; PP8997; TBC1D2A; TBC1D2 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
928
Cellular Location
Cytoplasm. Cytoplasmic vesicle. Cell junction
Tissue Location
Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TBC1D2 blocking peptide
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
54,419 Da
NCBI Official Full Name
TBC1 domain family member 2A
NCBI Official Synonym Full Names
TBC1 domain family member 2
NCBI Official Symbol
TBC1D2
NCBI Official Synonym Symbols
PARIS1; PARIS-1; TBC1D2A
NCBI Protein Information
TBC1 domain family member 2A
UniProt Protein Name
TBC1 domain family member 2A
Protein Family
UniProt Gene Name
TBC1D2
UniProt Synonym Gene Names
PARIS1; PP8997; TBC1D2A; PARIS-1
UniProt Entry Name
TBD2A_HUMAN
Uniprot Description
TBC1D2: a putative GTPase activating protein for Rab family protein(s). Expressed in a broad range of tissues. Differentially expressed in prostate normal and cancer cells.
Protein type: GAPs; GAPs, Rab
Chromosomal Location of Human Ortholog: 9q22.33
Cellular Component: cell junction; cytoplasmic vesicle; endomembrane system
Molecular Function: cadherin binding; GTPase activator activity; protein binding; Rab GTPase binding
Biological Process: intracellular protein transport; positive regulation of GTPase activity; regulation of vesicle fusion
Research Articles on TBC1D2
Similar Products
Product Notes
The TBC1D2 tbc1d2 (Catalog #AAA9223597) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TBC1D2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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