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TASP1 blocking peptide

TASP1 Antibody (C-term) Blocking Peptide

Gene Names
TASP1; C20orf13; dJ585I14.2
Synonyms
TASP1; TASP1 Antibody (C-term) Blocking Peptide; Threonine aspartase 1; Taspase-1; 3425-; Threonine aspartase subunit alpha; Threonine aspartase subunit beta; C20orf13; TASP1 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human TASP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Sequence Length
420
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TASP1 blocking peptide
Protease involved in KMT2A/MLL1 processing and, consequently, in the correct expression of the early HOXA gene cluster.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
15,946 Da
NCBI Official Full Name
Threonine aspartase 1
NCBI Official Synonym Full Names
taspase 1
NCBI Official Symbol
TASP1
NCBI Official Synonym Symbols
C20orf13; dJ585I14.2
NCBI Protein Information
threonine aspartase 1
UniProt Protein Name
Threonine aspartase 1
Protein Family
UniProt Gene Name
TASP1
UniProt Synonym Gene Names
C20orf13; Taspase-1
UniProt Entry Name
TASP1_HUMAN

NCBI Description

This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

TASP1: Protease involved in MLL processing and, consequently, in the correct expression of the early HOXA gene cluster. Belongs to the Ntn-hydrolase family.

Protein type: EC 3.4.25.-; Protease

Chromosomal Location of Human Ortholog: 20p12.1

Molecular Function: threonine endopeptidase activity

Biological Process: positive regulation of transcription, DNA-dependent; proteolysis

Research Articles on TASP1

Similar Products

Product Notes

The TASP1 tasp1 (Catalog #AAA9219825) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TASP1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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