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SNX4 blocking peptide

SNX4 Antibody (C-term) Blocking peptide

Gene Names
SNX4; ATG24B
Synonyms
SNX4; SNX4 Antibody (C-term) Blocking peptide; Sorting nexin-4; SNX4 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
450
Cellular Location
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also detected on a juxtanuclear endocytic recycling compartment (ERC)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SNX4 blocking peptide
May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
35,611 Da
NCBI Official Full Name
Sorting nexin-4
NCBI Official Synonym Full Names
sorting nexin 4
NCBI Official Symbol
SNX4
NCBI Official Synonym Symbols
ATG24B
NCBI Protein Information
sorting nexin-4
UniProt Protein Name
Sorting nexin-4
Protein Family
UniProt Gene Name
SNX4
UniProt Entry Name
SNX4_HUMAN

NCBI Description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012]

Uniprot Description

SNX4: May be involved in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Belongs to the sorting nexin family.

Chromosomal Location of Human Ortholog: 3q21.2

Cellular Component: cytoplasm; cytoplasmic dynein complex; early endosome membrane; extrinsic to membrane; membrane; plasma membrane; protein complex; SNARE complex

Molecular Function: epidermal growth factor receptor binding; insulin receptor binding; phosphoinositide binding; protein binding

Biological Process: endocytic recycling; endocytosis; protein transport; vesicle organization and biogenesis

Research Articles on SNX4

Similar Products

Product Notes

The SNX4 snx4 (Catalog #AAA9219458) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SNX4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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