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SLC6A17 blocking peptide

SLC6A17 Antibody (C-term) Blocking peptide

Gene Names
SLC6A17; NTT4; MRT48
Synonyms
SLC6A17; SLC6A17 Antibody (C-term) Blocking peptide; Sodium-dependent neutral amino acid transporter SLC6A17; Sodium-dependent neurotransmitter transporter NTT4; Solute carrier family 6 member 17; NTT4; SLC6A17 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of SLC6A17. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
727
Cellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SLC6A17 blocking peptide
Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
81,001 Da
NCBI Official Full Name
Sodium-dependent neutral amino acid transporter SLC6A17
NCBI Official Synonym Full Names
solute carrier family 6 member 17
NCBI Official Symbol
SLC6A17
NCBI Official Synonym Symbols
NTT4; MRT48
NCBI Protein Information
sodium-dependent neutral amino acid transporter SLC6A17
UniProt Protein Name
Sodium-dependent neutral amino acid transporter SLC6A17
UniProt Gene Name
SLC6A17
UniProt Synonym Gene Names
NTT4
UniProt Entry Name
S6A17_HUMAN

NCBI Description

The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC6A17: Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A17 subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: integral to plasma membrane; synaptic vesicle

Molecular Function: amino acid transmembrane transporter activity

Biological Process: alanine transport; brain development; glycine transport; leucine transport; neutral amino acid transport; proline transport

Disease: Mental Retardation, Autosomal Recessive 48

Research Articles on SLC6A17

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Product Notes

The SLC6A17 slc6a17 (Catalog #AAA9219961) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SLC6A17, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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