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SLC39A14 blocking peptide

SLC39A14 Antibody (N-term) Blocking Peptide

Gene Names
SLC39A14; NET34; ZIP14; cig19; HMNDYT2; LZT-Hs4
Synonyms
SLC39A14; SLC39A14 Antibody (N-term) Blocking Peptide; Zinc transporter ZIP14; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; Solute carrier family 39 member 14; Zrt- and Irt-like protein 14; ZIP-14; KIAA0062; ZIP14; SLC39A14 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
492
Cellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, lamellipodium Note: Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae
Tissue Location
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SLC39A14 blocking peptide
May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
54,057 Da
NCBI Official Full Name
Zinc transporter ZIP14
NCBI Official Synonym Full Names
solute carrier family 39 member 14
NCBI Official Symbol
SLC39A14
NCBI Official Synonym Symbols
NET34; ZIP14; cig19; HMNDYT2; LZT-Hs4
NCBI Protein Information
zinc transporter ZIP14
UniProt Protein Name
Zinc transporter ZIP14
Protein Family
UniProt Gene Name
SLC39A14
UniProt Synonym Gene Names
KIAA0062; ZIP14; LZT-Hs4; ZIP-14
UniProt Entry Name
S39AE_HUMAN

NCBI Description

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

Uniprot Description

SLC39A14: May mediate cellular uptake of nontransferrin-bound iron. Broad-scope metal ion transporter with a preference for zinc uptake. Belongs to the ZIP transporter (TC 2.A.5) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: endoplasmic reticulum; Golgi apparatus; integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: cellular zinc ion homeostasis

Research Articles on SLC39A14

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Product Notes

The SLC39A14 slc39a14 (Catalog #AAA9221588) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SLC39A14, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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