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SGPL1 blocking peptide

SGPL1 Antibody (N-term) Blocking peptide

Gene Names
SGPL1; SPL; S1PL
Synonyms
SGPL1; SGPL1 Antibody (N-term) Blocking peptide; Sphingosine-1-phosphate lyase 1; S1PL; SP-lyase 1; SPL 1; hSPL; Sphingosine-1-phosphate aldolase; KIAA1252; SGPL1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
568
Cellular Location
Endoplasmic reticulum membrane; Single-pass type III membrane protein
Tissue Location
Found in liver and kidney.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SGPL1 blocking peptide
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
63,524 Da
NCBI Official Full Name
Sphingosine-1-phosphate lyase 1
NCBI Official Synonym Full Names
sphingosine-1-phosphate lyase 1
NCBI Official Symbol
SGPL1
NCBI Official Synonym Symbols
SPL; S1PL
NCBI Protein Information
sphingosine-1-phosphate lyase 1
UniProt Protein Name
Sphingosine-1-phosphate lyase 1
UniProt Gene Name
SGPL1
UniProt Synonym Gene Names
KIAA1252; S1PL; SP-lyase 1; SPL 1; hSPL
UniProt Entry Name
SGPL1_HUMAN

Uniprot Description

SGPL1: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.

Protein type: Apoptosis; Lipid Metabolism - sphingolipid; EC 4.1.2.27; Lyase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q21

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane

Molecular Function: protein binding; sphinganine-1-phosphate aldolase activity

Biological Process: ceramide metabolic process; fatty acid metabolic process; sphingolipid biosynthetic process; sphingolipid catabolic process

Research Articles on SGPL1

Similar Products

Product Notes

The SGPL1 sgpl1 (Catalog #AAA9219364) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SGPL1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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