SERTAD2 blocking peptide
SERTAD2 Antibody (N-term) Blocking Peptide
Gene Names
SERTAD2; Sei-2; TRIP-Br2
Synonyms
SERTAD2; SERTAD2 Antibody (N-term) Blocking Peptide; SERTA domain-containing protein 2; Transcriptional regulator interacting with the PHD-bromodomain 2; TRIP-Br2; KIAA0127; SERTAD2 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
314
Cellular Location
Nucleus. Cytoplasm. Note: Exported out of the nucleus via its NES in a XPO1-dependent manner. Once in the cytoplasm, is degraded by the proteasome
Tissue Location
Expressed in adipose tissue.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SERTAD2 blocking peptide
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F- target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
33,897 Da
NCBI Official Full Name
SERTA domain-containing protein 2
NCBI Official Synonym Full Names
SERTA domain containing 2
NCBI Official Symbol
SERTAD2
NCBI Official Synonym Symbols
Sei-2; TRIP-Br2
NCBI Protein Information
SERTA domain-containing protein 2
UniProt Protein Name
SERTA domain-containing protein 2
Protein Family
UniProt Gene Name
SERTAD2
UniProt Synonym Gene Names
KIAA0127; TRIP-Br2
UniProt Entry Name
SRTD2_HUMAN
Uniprot Description
SERTAD2: Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors.
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: cytoplasm; nucleus
Biological Process: negative regulation of cell growth
Research Articles on SERTAD2
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Product Notes
The SERTAD2 sertad2 (Catalog #AAA9222960) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SERTAD2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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