SASS6 blocking peptide
SASS6 Antibody (Center) Blocking Peptide
Gene Names
SASS6; SAS6; SAS-6; MCPH14
Synonyms
SASS6; SASS6 Antibody (Center) Blocking Peptide; Spindle assembly abnormal protein 6 homolog; HsSAS-6; SAS6; SASS6 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
657
Cellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note: Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles (By similarity). Component of the centrosome. Associated only transiently with nascent procentrioles during centriole biogenesis.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for SASS6 blocking peptide
Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
74,397 Da
NCBI Official Full Name
Spindle assembly abnormal protein 6 homolog
NCBI Official Synonym Full Names
SAS-6 centriolar assembly protein
NCBI Official Symbol
SASS6
NCBI Official Synonym Symbols
SAS6; SAS-6; MCPH14
NCBI Protein Information
spindle assembly abnormal protein 6 homolog
UniProt Protein Name
Spindle assembly abnormal protein 6 homolog
Protein Family
UniProt Gene Name
SASS6
UniProt Synonym Gene Names
SAS6; HsSAS-6
UniProt Entry Name
SAS6_HUMAN
NCBI Description
SAS6 is necessary for centrosome duplication and functions during procentriole formation; SAS6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle Strnad et al., (2007) [PubMed 17681132].[supplied by OMIM, Mar 2008]
Uniprot Description
SAS6: Required for centrosome duplication. Overexpression results in excess foci-bearing centriolar markers.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 1p21.2
Cellular Component: centriole; centrosome
Molecular Function: protein binding
Biological Process: centriole replication; centrosome duplication
Disease: Microcephaly 14, Primary, Autosomal Recessive
Research Articles on SASS6
Similar Products
Product Notes
The SASS6 sass6 (Catalog #AAA9223095) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SASS6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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