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RUSC1 blocking peptide

RUSC1 Peptide

Gene Names
RUSC1; NESCA
Applications
Blocking (BL)
Synonyms
RUSC1; RUSC1 Peptide; NESCA; RUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; Nesca; RUN and SH3 domain containing 1; RUSC1 blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
902
Applicable Applications for RUSC1 blocking peptide
Blocking (BL)
Application Notes
RUSC1 peptide is used for blocking the activity of RUSC1 antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
17 amino acids near the carboxy terminus of human RUSC1.
Preparation and Storage
Store RUSC1 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
85,216 Da
NCBI Official Full Name
RUN and SH3 domain-containing protein 1 isoform a
NCBI Official Synonym Full Names
RUN and SH3 domain containing 1
NCBI Official Symbol
RUSC1
NCBI Official Synonym Symbols
NESCA
NCBI Protein Information
RUN and SH3 domain-containing protein 1; new molecule containing SH3 at the carboxy-terminus
UniProt Protein Name
RUN and SH3 domain-containing protein 1
UniProt Gene Name
RUSC1
UniProt Synonym Gene Names
NESCA; Nesca
UniProt Entry Name
RUSC1_HUMAN

Uniprot Description

RUSC1: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q21-q22

Cellular Component: microtubule cytoskeleton; Golgi apparatus; microtubule; postsynaptic membrane; cytoplasm; cytoplasmic membrane-bound vesicle; early endosome; postsynaptic density; cytoplasmic vesicle; cell junction; nucleus

Molecular Function: protein binding; SH3/SH2 adaptor activity; actin binding

Biological Process: protein polyubiquitination; positive regulation of signal transduction

Research Articles on RUSC1

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Product Notes

The RUSC1 rusc1 (Catalog #AAA151791) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RUSC1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). RUSC1 peptide is used for blocking the activity of RUSC1 antibody. Researchers should empirically determine the suitability of the RUSC1 rusc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RUSC1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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