ROPN1 blocking peptide

ROPN1 Blocking Peptide (Center)

Gene Names

ROPN1; CT91; ODF6; ROPN1A; RHPNAP1; ropporin

Synonyms

ROPN1; ROPN1 Blocking Peptide (Center); Ropporin-1A; Cancer/testis antigen 91; CT91; Rhophilin-associated protein 1A; ROPN1A; ROPN1 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 111-121 of HUMAN ROPN1

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

212

Cellular Location

Note: In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath (By similarity).

Tissue Location

Testis specific in adult. Overexpressed in hematologic tumor cells.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

NCBI GI #

74718687

NCBI GeneID

54763

UniProt Accession #

Q9HAT0; Q9UF38; D3DN99

Molecular Weight

6,711 Da

NCBI Official Full Name

Ropporin-1A

NCBI Official Synonym Full Names

rhophilin associated tail protein 1

NCBI Official Symbol

ROPN1

NCBI Official Synonym Symbols

CT91; ODF6; ROPN1A; RHPNAP1; ropporin

NCBI Protein Information

ropporin-1A

UniProt Protein Name

Ropporin-1A

Protein Family

Ropporin

UniProt Gene Name

ROPN1

UniProt Synonym Gene Names

ROPN1A; CT91

UniProt Entry Name

ROP1A_HUMAN

NCBI Description

The protein encoded by this gene is found in the fibrous sheath of spermatazoa, where it interacts with rhophilin, a Rho GTPase binding protein. The encoded protein also can bind an A-kinase anchoring protein (AKAP110) and a calcium-binding tyrosine phosphorylation-regulated protein (CABYR). This protein may be involved in sperm motility and has been shown to be a cancer-testis antigen in hematologic malignancies. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

Uniprot Description

ROPN1: Belongs to the ropporin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, regulatory subunit; Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 3q21.1

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Research Articles on ROPN1

1. Ropporin gene expression is related to the sperm motility. Its abnormal expression in the sperm of asthenozoospermic men with varicocele is associated with impaired sperm motility that is improved after varicocelectomy.

Similar Products

Product Notes

The ROPN1 ropn1 (Catalog #AAA9230341) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ROPN1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Loading...

ROPN1 blocking peptide