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RBM11 blocking peptide

RBM11 Antibody (N-term) Blocking Peptide

Synonyms
RBM11; RBM11 Antibody (N-term) Blocking Peptide; Splicing regulator RBM11; RNA-binding motif protein 11; RBM11 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
281
Cellular Location
Nucleus, nucleoplasm. Nucleus speckle. Note: Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles
Tissue Location
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for RBM11 blocking peptide
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
26,465 Da
NCBI Official Full Name
Splicing regulator RBM11
NCBI Official Synonym Full Names
RNA binding motif protein 11
NCBI Official Symbol
RBM11
NCBI Protein Information
splicing regulator RBM11
UniProt Protein Name
Splicing regulator RBM11
Protein Family
UniProt Gene Name
RBM11
UniProt Entry Name
RBM11_HUMAN

Uniprot Description

RBM11: Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 21q11

Cellular Component: nuclear speck; nucleoplasm; nucleus

Molecular Function: poly(U) binding; protein binding; protein homodimerization activity

Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome

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Product Notes

The RBM11 rbm11 (Catalog #AAA9222710) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RBM11, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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