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RAB5C blocking peptide

RAB5C Antibody (C-term) Blocking peptide

Gene Names
RAB5C; RABL; L1880; RAB5L; RAB5CL
Synonyms
RAB5C; RAB5C Antibody (C-term) Blocking peptide; Ras-related protein Rab-5C; L1880; RAB5L; RABL; RAB5C blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of RAB5C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
216
Cellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for RAB5C blocking peptide
Protein transport. Probably involved in vesicular traffic (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
27,036 Da
NCBI Official Full Name
Ras-related protein Rab-5C
NCBI Official Synonym Full Names
RAB5C, member RAS oncogene family
NCBI Official Symbol
RAB5C
NCBI Official Synonym Symbols
RABL; L1880; RAB5L; RAB5CL
NCBI Protein Information
ras-related protein Rab-5C
UniProt Protein Name
Ras-related protein Rab-5C
Protein Family
UniProt Gene Name
RAB5C
UniProt Synonym Gene Names
RABL
UniProt Entry Name
RAB5C_HUMAN

NCBI Description

Members of the Rab protein family are small GTPases of the Ras superfamily that are thought to ensure fidelity in the process of docking and/or fusion of vesicles with their correct acceptor compartment (Han et al., 1996 [PubMed 8646882]).[supplied by OMIM, Nov 2010]

Uniprot Description

RAB5C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.

Protein type: Motility/polarity/chemotaxis; G protein, monomeric; G protein; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 17q21.2

Cellular Component: early endosome; endocytic vesicle; intracellular membrane-bound organelle; lipid particle; lysosomal membrane; plasma membrane

Molecular Function: GDP binding; GTPase activity; protein binding

Biological Process: plasma membrane to endosome transport; regulation of endocytosis

Research Articles on RAB5C

Similar Products

Product Notes

The RAB5C rab5c (Catalog #AAA9219916) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RAB5C, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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