PDIA6 blocking peptide
PDIA6 Antibody (Center K159) Blocking Peptide
Gene Names
PDIA6; P5; ERP5; TXNDC7
Synonyms
PDIA6; PDIA6 Antibody (Center K159) Blocking Peptide; Protein disulfide-isomerase A6; Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7; ERP5; P5; TXNDC7; PDIA6 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human PDIA6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
440
Cellular Location
Endoplasmic reticulum lumen. Cell membrane. Melanosome Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location
Expressed in platelets (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PDIA6 blocking peptide
May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
53,261 Da
NCBI Official Full Name
Protein disulfide-isomerase A6
NCBI Official Synonym Full Names
protein disulfide isomerase family A member 6
NCBI Official Symbol
PDIA6
NCBI Official Synonym Symbols
P5; ERP5; TXNDC7
NCBI Protein Information
protein disulfide-isomerase A6
UniProt Protein Name
Protein disulfide-isomerase A6
Protein Family
UniProt Gene Name
PDIA6
UniProt Synonym Gene Names
ERP5; P5; TXNDC7; ER protein 5; ERp5
UniProt Entry Name
PDIA6_HUMAN
NCBI Description
Protein disulfide isomerases (EC 5.3.4.1), such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization of disulfide bonds in proteins and are thought to play a role in folding of disulfide-bonded proteins (Hayano and Kikuchi, 1995 [PubMed 7590364]).[supplied by OMIM, Mar 2008]
Uniprot Description
May function as a chaperone that inhibits aggregation of misfolded proteins. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
Research Articles on PDIA6
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Product Notes
The PDIA6 pdia6 (Catalog #AAA9226235) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PDIA6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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