PARP10 blocking peptide
PARP10 Peptide - middle region
Target Description: Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors.Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-13 DA124793.1 1-13 14-3145 AK222914.1 1-3132 3146-3504 BC014229.2 1134-1492 3505-3525 AI470346.1 1-21 c
NCBI and Uniprot Product Information
NCBI Description
Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008]
Uniprot Description
PARP10: May play a role in cell proliferation. May be required for the maintenance of cell cycle progression.
Protein type: EC 2.4.2.30; Nucleolus; Transferase
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleolus; nucleus
Molecular Function: NAD+ ADP-ribosyltransferase activity; protein binding
Biological Process: negative regulation of fibroblast proliferation; negative regulation of NF-kappaB transcription factor activity; negative regulation of protein import into nucleus, translocation; negative regulation of viral genome replication; protein ADP-ribosylation
Research Articles on PARP10
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Product Notes
The PARP10 parp10 (Catalog #AAA3231527) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PARP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PARP10 parp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARP10, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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