NUP93 blocking peptide

NUP93 Blocking Peptide (N-Term)

• Synonyms: NUP93; NUP93 Blocking Peptide (N-Term); Nuclear pore complex protein Nup93; 93 kDa nucleoporin; Nucleoporin Nup93; KIAA0095; NUP93 blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 40-54 of HUMAN NUP93
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 819

• Cellular Location: Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Note: Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NUP93 blocking peptide

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.

NCBI and Uniprot Product Information

• NCBI GI #: 218546716
• NCBI GeneID: 510004
• UniProt Accession #: Q8N1F7; Q14705; B3KPQ8; A5PJZ5
• Molecular Weight: 79,882 Da
• NCBI Official Full Name: Nuclear pore complex protein Nup93
• NCBI Official Symbol: NUP93
• NCBI Protein Information: nuclear pore complex protein Nup93
• UniProt Protein Name: Nuclear pore complex protein Nup93
• Protein Family: Nuclear pore complex protein
• UniProt Gene Name: NUP93
• UniProt Synonym Gene Names: KIAA0095
• UniProt Entry Name: NUP93_HUMAN

Uniprot Description

NUP93: a nuclear pore protein (nucleoporin) required for correct nuclear pore assembly. The nuclear pore complex, comprised of approximately 30 nucleoporins, mediates the exchange of macromolecules across the nuclear envelope. It is comprised of approximately 30 proteins termed nucleoporins that are each present in multiple copies. Belongs to the nucleoporin interacting component (NIC) family.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: membrane; nuclear envelope; nuclear membrane; nuclear pore

Molecular Function: structural constituent of nuclear pore

Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; nuclear pore complex assembly; poly(A)+ mRNA export from nucleus; positive regulation of defense response to virus by host; protein import into nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription