NUP107 blocking peptide

NUP107 Blocking Peptide

Cat. Num. AAA9624421

• Gene Names: NUP107; NUP84; NPHS11
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: NUP107; NUP107 Blocking Peptide; 107 kDa nucleoporin; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP84; yeast; homolog of; OTTHUMP00000240604; OTTHUMP00000240606; NUP107 blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for NUP107 blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NUP107 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 1056849713
• NCBI GeneID: 57122
• NCBI Accession #: NP_001317121.1
• NCBI GenBank Nucleotide #: NM_001330192.1
• UniProt Accession #: P57740; Q6PJE1; B4DZ67
• Molecular Weight: 79,971 Da
• NCBI Official Full Name: nuclear pore complex protein Nup107 isoform 2
• NCBI Official Synonym Full Names: nucleoporin 107
• NCBI Official Symbol: NUP107
• NCBI Official Synonym Symbols: NUP84; NPHS11
• NCBI Protein Information: nuclear pore complex protein Nup107
• UniProt Protein Name: Nuclear pore complex protein Nup107
• Protein Family: Nucleoporin
• UniProt Gene Name: NUP107
• UniProt Entry Name: NU107_HUMAN

NCBI Description

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

NUP107: Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex. Belongs to the nucleoporin Nup84/Nup107 family.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: nucleoplasm; kinetochore; centrosome; nuclear membrane; membrane; nuclear pore; nuclear envelope; cytosol

Molecular Function: protein binding; structural constituent of nuclear pore; nucleocytoplasmic transporter activity

Biological Process: nuclear pore complex assembly; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; mRNA export from nucleus; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport