NOLC1 blocking peptide
NOLC1 Blocking Peptide
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NCBI and Uniprot Product Information
Uniprot Description
NOLC1: Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Nucleolus; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 10q24.32
Cellular Component: nucleoplasm; Cajal body; cytoplasm; nucleolus
Molecular Function: protein binding; GTP binding; ATP binding
Biological Process: mitosis; cell cycle; rRNA processing; nucleolus organization and biogenesis