NDUFS3 blocking peptide

NDUFS3 Blocking Peptide (C-term)

Gene Names

NDUFS3; CI-30

Synonyms

NDUFS3; NDUFS3 Blocking Peptide (C-term); NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit; NDUFS3 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 251-264 of HUMAN NDUFS3

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

264

Cellular Location

Mitochondrion inner membrane.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NDUFS3 blocking peptide

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

NCBI and Uniprot Product Information

NCBI GI #

6166589

NCBI GeneID

4722

UniProt Accession #

O75489; Q9UNQ8; B2R9J1; B4DFM8

Molecular Weight

14,679 Da

NCBI Official Full Name

NADH dehydrogenase

NCBI Official Synonym Full Names

NADH:ubiquinone oxidoreductase core subunit S3

NCBI Official Symbol

NDUFS3

NCBI Official Synonym Symbols

CI-30

NCBI Protein Information

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

UniProt Protein Name

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

UniProt Gene Name

NDUFS3

UniProt Synonym Gene Names

CI-30kD

UniProt Entry Name

NDUS3_HUMAN

NCBI Description

This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

Uniprot Description

NDUFS3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 30 kDa subunit family.

Protein type: EC 1.6.5.3; Oxidoreductase; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial

Chromosomal Location of Human Ortholog: 11p11.11

Cellular Component: mitochondrial matrix; mitochondrial membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleus

Molecular Function: NADH dehydrogenase activity; protein binding

Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; negative regulation of cell growth; substantia nigra development

Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency

Research Articles on NDUFS3

1. High NDUFS3 expression is associated with IgA nephropathy.

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Product Notes

The NDUFS3 ndufs3 (Catalog #AAA9229372) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NDUFS3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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NDUFS3 blocking peptide