MYO6 blocking peptide
MYO6 Antibody (C-term R1181) Blocking peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Uniprot Description
MYO6: a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins.
Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 6q13
Cellular Component: cell cortex; clathrin-coated endocytic vesicle; cytoplasm; cytoplasmic membrane-bound vesicle; cytosol; DNA-directed RNA polymerase II, holoenzyme; endocytic vesicle; filamentous actin; Golgi apparatus; lysosomal membrane; membrane; nuclear membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; ruffle; unconventional myosin complex
Molecular Function: actin binding; actin filament binding; ADP binding; calmodulin binding; motor activity; protein binding
Biological Process: actin filament-based movement; DNA damage response, signal transduction by p53 class mediator; endocytosis; intracellular protein transport; positive regulation of transcription from RNA polymerase II promoter; regulation of secretion
Disease: Deafness, Autosomal Dominant 22; Deafness, Autosomal Recessive 37
Research Articles on MYO6
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Product Notes
The MYO6 myo6 (Catalog #AAA9218478) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MYO6, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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