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MMRN2 blocking peptide

MMRN2 Antibody (C-term) Blocking peptide

Gene Names
MMRN2; EMILIN3; EMILIN-3; ENDOGLYX-1
Synonyms
MMRN2; MMRN2 Antibody (C-term) Blocking peptide; Multimerin-2; EMILIN-3; Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3; EndoGlyx-1 p125/p140 subunit; EMILIN3; MMRN2 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
949
Cellular Location
Secreted, extracellular space, extracellular matrix
Tissue Location
Endothelium..
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MMRN2 blocking peptide
Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
104,409 Da
NCBI Official Full Name
multimerin-2
NCBI Official Synonym Full Names
multimerin 2
NCBI Official Symbol
MMRN2
NCBI Official Synonym Symbols
EMILIN3; EMILIN-3; ENDOGLYX-1
NCBI Protein Information
multimerin-2
UniProt Protein Name
Multimerin-2
Protein Family
UniProt Gene Name
MMRN2
UniProt Synonym Gene Names
EMILIN3; Elastin microfibril interfacer 3
UniProt Entry Name
MMRN2_HUMAN

NCBI Description

This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]

Uniprot Description

MMRN2: Heteromer of p110, p125, p140 and p200 subunits; disulfide-linked.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q23.2

Cellular Component: extracellular space

Molecular Function: protein binding

Biological Process: negative regulation of vascular endothelial growth factor receptor signaling pathway

Research Articles on MMRN2

Similar Products

Product Notes

The MMRN2 mmrn2 (Catalog #AAA9219612) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MMRN2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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