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MGST2 blocking peptide

MGST2 Antibody (C-term) Blocking Peptide

Gene Names
MGST2; GST2; MGST-II
Synonyms
MGST2; MGST2 Antibody (C-term) Blocking Peptide; Microsomal glutathione S-transferase 2; Microsomal GST-2; Microsomal GST-II; GST2; MGST2 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human MGST2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
147
Cellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein Microsome membrane; Multi-pass membrane protein
Tissue Location
Liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. Very low expression in lung, brain, placenta and bone marrow
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MGST2 blocking peptide
Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4- dinitrobenzene with reduced glutathione.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
8,359 Da
NCBI Official Full Name
Microsomal glutathione S-transferase 2
NCBI Official Synonym Full Names
microsomal glutathione S-transferase 2
NCBI Official Symbol
MGST2
NCBI Official Synonym Symbols
GST2; MGST-II
NCBI Protein Information
microsomal glutathione S-transferase 2
UniProt Protein Name
Microsomal glutathione S-transferase 2
UniProt Gene Name
MGST2
UniProt Synonym Gene Names
GST2; Microsomal GST-2
UniProt Entry Name
MGST2_HUMAN

NCBI Description

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

MGST2: Can catalyze the production of LTC4 from LTA4 and reduced glutathione. Can catalyze the conjugation of 1-chloro-2,4- dinitrobenzene with reduced glutathione. Belongs to the MAPEG family.

Protein type: Membrane protein, multi-pass; Transferase; Membrane protein, integral; Other Amino Acids Metabolism - glutathione; Endoplasmic reticulum; EC 2.5.1.18; Xenobiotic Metabolism - metabolism by cytochrome P450; Xenobiotic Metabolism - drug metabolism - cytochrome P450

Chromosomal Location of Human Ortholog: 4q28.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bound organelle; nuclear envelope; plasma membrane

Molecular Function: glutathione peroxidase activity; glutathione transferase activity; leukotriene-C4 synthase activity

Biological Process: glutathione biosynthetic process; leukotriene biosynthetic process; xenobiotic metabolic process

Research Articles on MGST2

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Product Notes

The MGST2 mgst2 (Catalog #AAA9227900) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MGST2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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