MEX3B blocking peptide

MEX3B Antibody (N-term) Blocking Peptide

• Gene Names: MEX3B; RKHD3; MEX-3B; RNF195
• Synonyms: MEX3B; MEX3B Antibody (N-term) Blocking Peptide; RNA-binding protein MEX3B; RING finger and KH domain-containing protein 3; RING finger protein 195; KIAA2009; RKHD3; RNF195; MEX3B blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 569

• Cellular Location: Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note: Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3
• Tissue Location: Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for MEX3B blocking peptide

RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms.

NCBI and Uniprot Product Information

• NCBI GI #: 74762391
• NCBI GeneID: 84206
• UniProt Accession #: Q6ZN04; Q4G0W1; Q8IVG2; Q9H0J0
• Molecular Weight: 16,780 Da
• NCBI Official Full Name: RNA-binding protein MEX3B
• NCBI Official Synonym Full Names: mex-3 RNA binding family member B
• NCBI Official Symbol: MEX3B
• NCBI Official Synonym Symbols: RKHD3; MEX-3B; RNF195
• NCBI Protein Information: RNA-binding protein MEX3B
• UniProt Protein Name: RNA-binding protein MEX3B
• Protein Family: RNA-binding protein
• UniProt Gene Name: MEX3B
• UniProt Synonym Gene Names: KIAA2009; RKHD3; RNF195
• UniProt Entry Name: MEX3B_HUMAN

NCBI Description

This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators. The encoded protein contains N-terminal nuclear export and nuclear localization signals and is exported from the cytoplasm to the nucleus. The protein binds to RNA via two KH domains and also colocalizes with MEX3A, Dcp1A decapping factor and Argonaute proteins within P (processing) bodies. [provided by RefSeq, Oct 2012]

Uniprot Description

RKHD3: RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 15q25.2

Molecular Function: calcium ion binding

Biological Process: protein amino acid autophosphorylation; protein amino acid phosphorylation