LPPL blocking peptide

LPPL Blocking Peptide

Cat. Num. AAA9622617

• Gene Names: CLC; GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN
• Applications: Blocking/Control
• Purity: The purity is >90%,tested by HPLC and MS.
• Synonyms: LPPL; LPPL Blocking Peptide; BSF3; Charcot Leyden crystal protein; Charcot-Leyden crystal protein; CLC; EC 3.1.1.5; Eosinophil lysophospholipase; Gal-10; Galectin-10; LGALS10; LGALS10A; LPPL HUMAN; LPPL_HUMAN; Lysolecithin acylhydrolase; MGC149659; LPPL blocking peptide

• Purity/Purification: The purity is >90%,tested by HPLC and MS.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

• Applicable Applications for LPPL blocking peptide: Blocking/Control
• Notes: For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for LPPL blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

• NCBI GI #: 20357559
• NCBI GeneID: 1178
• NCBI Accession #: NP_001819.2
• NCBI GenBank Nucleotide #: NM_001828.5
• UniProt Accession #: Q05315; Q0VDE3; C5HZ13; C5HZ14
• Molecular Weight: 16,453 Da
• NCBI Official Full Name: galectin-10
• NCBI Official Synonym Full Names: Charcot-Leyden crystal galectin
• NCBI Official Symbol: CLC
• NCBI Official Synonym Symbols: GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN
• NCBI Protein Information: galectin-10; Charcot-Leyden crystal protein; eosinophil lysophospholipase; galectin 10; lectin, galactoside-binding, soluble, 10; lysolecithin acylhydrolase
• UniProt Protein Name: Galectin-10
• Protein Family: Lipopeptide
• UniProt Gene Name: CLC
• UniProt Synonym Gene Names: LGALS10; LGALS10A; Gal-10; CLC
• UniProt Entry Name: LEG10_HUMAN

NCBI Description

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008]

Uniprot Description

CLC: May have both lysophospholipase and carbohydrate-binding activities.

Protein type: Phospholipase; EC 3.1.1.5

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: cytosol

Molecular Function: protein binding; carbohydrate binding; lysophospholipase activity

Biological Process: regulation of activated T cell proliferation; regulation of T cell cytokine production; multicellular organismal development; regulation of T cell anergy