KLHL2 blocking peptide
KLHL2 Antibody (N-term) Blocking Peptide
Gene Names
KLHL2; MAV; MAYVEN; ABP-KELCH
Synonyms
KLHL2; KLHL2 Antibody (N-term) Blocking Peptide; Kelch-like protein 2; Actin-binding protein Mayven; KLHL2 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
593
Cellular Location
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection. Cell projection, lamellipodium. Cytoplasm, cytosol. Note: A proportion colocalizes with the actin cytoskeleton. When over-expressed, colocalizes with NPTXR in perinuclear aggresomes (By similarity)
Tissue Location
Ubiquitous. Detected throughout the brain.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for KLHL2 blocking peptide
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
56,086 Da
NCBI Official Full Name
Kelch-like protein 2
NCBI Official Synonym Full Names
kelch like family member 2
NCBI Official Symbol
KLHL2
NCBI Official Synonym Symbols
MAV; MAYVEN; ABP-KELCH
NCBI Protein Information
kelch-like protein 2
UniProt Protein Name
Kelch-like protein 2
Protein Family
UniProt Gene Name
KLHL2
UniProt Entry Name
KLHL2_HUMAN
Uniprot Description
KLHL2: May play a role in organizing the actin cytoskeleton of the brain cells. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 4q21.2
Cellular Component: actin cytoskeleton; cytoplasm
Molecular Function: actin binding; protein binding; ubiquitin-protein ligase activity
Biological Process: protein ubiquitination
Research Articles on KLHL2
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Product Notes
The KLHL2 klhl2 (Catalog #AAA9222700) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "KLHL2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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