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ITGB8 blocking peptide

ITGB8 Blocking Peptide (Center)

Synonyms
ITGB8; ITGB8 Blocking Peptide (Center); Integrin beta-8; ITGB8 blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 197-211 of HUMAN ITGB8
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
769
Cellular Location
Membrane; Single-pass type I membrane protein
Tissue Location
Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ITGB8 blocking peptide
Integrin alpha-V/beta-8 is a receptor for fibronectin.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
71,284 Da
NCBI Official Full Name
Integrin beta-8
NCBI Official Synonym Full Names
integrin subunit beta 8
NCBI Official Symbol
ITGB8
NCBI Protein Information
integrin beta-8
UniProt Protein Name
Integrin beta-8
Protein Family
UniProt Gene Name
ITGB8
UniProt Entry Name
ITB8_HUMAN

NCBI Description

This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ITGB8: Integrin alpha-V/beta-8 is a receptor for fibronectin. Belongs to the integrin beta chain family.

Protein type: Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: cell surface; integrin complex; plasma membrane

Biological Process: cartilage development; cell adhesion; cell-matrix adhesion; extracellular matrix organization and biogenesis

Research Articles on ITGB8

Similar Products

Product Notes

The ITGB8 itgb8 (Catalog #AAA9229682) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ITGB8, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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