IL-20Ralpha blocking peptide
IL-20Ralpha (V222) Peptide
Applications
Blocking
Purity
Synthetic peptide IL-20Ralpha (V222). (Note: the amino acid sequence is proprietary).The purity is >98%.
Synonyms
IL-20Ralpha; IL-20Ralpha (V222) Peptide; Interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor class-II member 8; Cytokine receptor family 2 member 8; CRF2-8; IL-20R1; ZcytoR7; UNQ681/PRO1315; IL20RA; IL-20Ralpha blocking peptide
Specificity
This peptide can be used with studies using MBS3003788 IL-20Ralpha (V222) pAb.
Purity/Purification
Synthetic peptide IL-20Ralpha (V222). (Note: the amino acid sequence is proprietary).
The purity is >98%.
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
553
Applicable Applications for IL-20Ralpha blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for IL-20Ralpha blocking peptide
The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ralpha and IL-20Rbeta. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ralpha and IL-20Rbeta all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
interleukin-20 receptor subunit alpha
UniProt Protein Name
Interleukin-20 receptor subunit alpha
UniProt Gene Name
IL20RA
UniProt Synonym Gene Names
IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; CRF2-8
UniProt Entry Name
I20RA_HUMAN
Uniprot Description
IL20RA: The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. Belongs to the type II cytokine receptor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6q23.3
Cellular Component: plasma membrane; integral to membrane
Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-20 binding
Biological Process: regulation of bone resorption; cytokine and chemokine mediated signaling pathway
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Product Notes
The IL-20Ralpha il20ra (Catalog #AAA3003789) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL-20Ralpha can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the IL-20Ralpha il20ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-20Ralpha, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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