hnRNP C1/2 Blocking Peptide | hnRNP blocking peptide

hnRNP C1/2 (G256) Peptide

Cat. Num. AAA3001623

• Gene Names: HNRNPC; C1; C2; HNRNP; HNRPC; SNRPC
• Applications: Blocking
• Purity: Synthetic peptide hnRNP C1/2 (G256). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Synonyms: hnRNP C1/2; hnRNP C1/2 (G256) Peptide; hnRNP core protein A1-like protein; RP11-78J21.1; hnRNP blocking peptide

• Specificity: This peptide can be used with studies using MBS3001622 hnRNP C1/2 (G256) pAb.
• Purity/Purification: Synthetic peptide hnRNP C1/2 (G256). (Note: the amino acid sequence is proprietary).; The purity is >98%.
• Form/Format: 1 mg/ml in DI water.
• Sequence Length: 306

• Applicable Applications for hnRNP blocking peptide: Blocking
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Related Product Information for hnRNP blocking peptide

The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP C1 and C2 are encoded by one gene; the two alternatively spliced transcript variants have been described.

NCBI and Uniprot Product Information

• NCBI GI #: 117190192
• NCBI GeneID: 3183
• NCBI Accession #: NP_001070910.1
• NCBI GenBank Nucleotide #: NP_001070910.1
• UniProt Accession #: P07910
• NCBI Official Full Name: heterogeneous nuclear ribonucleoproteins C1/C2 isoform a
• NCBI Official Synonym Full Names: heterogeneous nuclear ribonucleoprotein C
• NCBI Official Symbol: HNRNPC
• NCBI Official Synonym Symbols: C1; C2; HNRNP; HNRPC; SNRPC
• NCBI Protein Information: heterogeneous nuclear ribonucleoproteins C1/C2
• UniProt Protein Name: Heterogeneous nuclear ribonucleoproteins C1/C2
• Protein Family: Heterogeneous nuclear ribonucleoprotein
• UniProt Gene Name: HNRNPC
• UniProt Synonym Gene Names: HNRPC; hnRNP C1/C2
• UniProt Entry Name: HNRPC_HUMAN

NCBI Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

hnRNP C1/C2: a heterogeneous nuclear ribonucleoprotein. May play a role in ribonucleosome assembly by neutralizing basic proteins such as A and B core hnRNP. Contains 1 RNA recognition motif (RRM) domain. Two alternatively spliced isoforms have been described.

Protein type: RNA-binding; Spliceosome; RNA splicing

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm; spliceosome; protein complex; membrane; nuclear chromatin; nucleus; cytosol

Molecular Function: identical protein binding; protein binding; nucleosomal DNA binding; mRNA 3'-UTR binding; RNA binding; nucleotide binding; poly(U) binding

Biological Process: nuclear mRNA splicing, via spliceosome; osteoblast differentiation; RNA splicing; ATP-dependent chromatin remodeling; gene expression